Name : TANK Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9576578056
| Long name | FITC Conjugated, TANK Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TANK |
| Specificity | This is a highly specific antibody against TANK |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human TANK |
| Gene ID number | 10010 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | For example, Specifically, TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, and inhibit LMP1-mediated NF kappa B activation, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB, or TRAF3, the Epstein Barr virus transforming protein, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm, this protein can block TRAF2 binding to LMP1, TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | I-TRAF |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TANK Conjugated |
| Short name | FITC Conjugated, TANK Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, TANK (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11562 |
| Gene | TANK |
| Long gene name | TRAF family member associated NFKB activator |
| Synonyms gene | TRAF2 |
| Synonyms gene name | TRAF family member-associated NFKB activator |
| Locus | 2q24, 2 |
| Discovery year | 1997-06-12 |
| GenBank acession | U59863 |
| Entrez gene record | 10010 |
| Pubmed identfication | 8710854 8855313 |
| RefSeq identity | NM_133484 |
| Havana BLAST/BLAT | OTTHUMG00000132037 |