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Tankyrase Antibody

Tankyrase Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTankyrase Primary Polyclonal Antibody
Also known asTankyrase PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTankyrase
SpecificityThis is a highly specific antibody against Tankyrase
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range1140-1171/1327
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tankyrase
Gene ID number8658
Swiss ProtO95271
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, Also mediates PARsylation of BLZF1 and CASC3, Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI, May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles, May be involved in spindle pole assembly through PARsylation of NUMA1, Mediates PARsylation of TERF1, Stimulates 26S proteasome activity, followed by recruitment of RNF146 and subsequent ubiquitination, telomere length and vesicle trafficking, thereby contributing to the regulation of telomere length, which mediates their ubiquitination and subsequent degradation, Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ADP-ribosyltransferase diphtheria toxin-like 5, ARTD5, PARP-5a, PARP5A, PARPL, Poly [ADP-ribose] polymerase 5A, TANK1, TINF1, TNKS, TNKS-1, TNKS1, TRF1-interacting ankyrin-related ADP-ribose polymerase, Tankyrase I, Tankyrase-1, pART5, TIN1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTankyrase
Short nameTankyrase Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTankyrase (Antibody to)
Alternative techniqueantibodies
Identity 19081
Gene TNKS1BP1
Long gene name tankyrase 1 binding protein 1
Synonyms gene name 182kDa , tankyrase 1 binding protein 1
Synonyms TAB182 KIAA1741 FLJ45975
Locus 11q12, 1
Discovery year 2002-08-06
GenBank acession AB051528
Entrez gene record 85456
Pubmed identfication 11854288
RefSeq identity NM_033396
Havana BLAST/BLAT OTTHUMG00000167022

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