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Tap1 Antibody, ALEXA FLUOR 488

Tap1 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Tap1 Polyclonal Antibody
Also known asAnti-Tap1 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTap1
SpecificityThis is a highly specific antibody against Tap1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range525-575/808
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tap1/ABCB2
Gene ID Number6890
Swiss ProtQ03518
Tested applications IF(ICC), IF(IHC-P), FCM
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Also acts as a molecular scaffold for the final stage of MHC class I folding, Expression of TAP1 is down-regulated by human Epstein-Barr virus vIL-1 protein, Inhibited by human adenovirus E3-19K glycoprotein, Inhibited by human cytomegalovirus US6 glycoprotein, Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, Nascent MHC class I molecules associate with TAP via tapasin, namely the binding of peptide, preventing MHC class I/TAP association, thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules, which binds the TAP complex and acts as a tapasin inhibitor, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding, which blocks the peptide-binding site of TAP, Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms XXbac-BPG246D15, 8 TAP1-AS1
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Tap1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetTap1
Short nameTap1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, adenosine triphosphate-binding cassette, sub-family B (multi-drug-resistant/TAP) (Antibody to), transporter 1
Alternative techniqueantibodies
Identity 39758
Gene PSMB8-AS1
Long gene name PSMB8 antisense RNA 1 (head to head)
Synonyms gene TAPSAR1
Synonyms gene name TAP1 and PSMB8 antisense RNA 1
Locus 6p21, 32
Discovery year 2013-07-25
Entrez gene record 100507463
RefSeq identity NR_037173
Havana BLAST/BLAT OTTHUMG00000140123

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