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TARDBP Antibody, FITC Conjugated

TARDBP Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, TARDBP Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTARDBP
SpecificityThis is a highly specific antibody against TARDBP
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range120-170/414
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human TDP-43
Gene ID number23435
Swiss ProtQ13148
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat, Involved in the regulation of CFTR splicing, It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon, May also be involved in microRNA biogenesis, Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR, The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis, apoptosis and cell division, DNA and RNA-binding protein which regulates transcription and splicing
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms TDP-43 ALS10
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTARDBP Conjugated
Short name FITC Conjugated, TARDBP Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TARDBP (Antibody to)
Alternative techniqueantibodies
Identity 11571
Gene TARDBP
Long gene name TAR DNA binding protein
Locus 1p36, 22
Discovery year 2000-01-28
GenBank acession U23731
Entrez gene record 23435
Pubmed identfication 7745706
RefSeq identity NM_007375
Classification RNA binding motif containing
Havana BLAST/BLAT OTTHUMG00000002120
Locus Specific Databases ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_659

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