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TAU Antibody

TAU Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTAU
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the TAU antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TAU antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P10636
PurityPurified
Description Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, [UniProt], and might be involved in the establishment and maintenance of neuronal polarity, suggesting that tau functions as a linker protein between both, TAU/MAPT promotes microtubule assembly and stability
ImmunogenA portion of amino acids 677-707 from the human protein was used as the immunogen for this TAU antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TAU antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTAU
Short nameTAU Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTaurine (Antibody to)
Alternative techniqueantibodies
Identity 6893
Gene MAPT
Long gene name microtubule associated protein tau
Synonyms gene DDPAC MAPTL
Synonyms MTBT1 tau PPND FTDP-17 TAU MSTD MTBT2 FLJ31424 MGC138549 PPP1R103
Synonyms name G protein beta1/gamma2 subunit-interacting factor 1 microtubule-associated protein tau, isoform 4 protein phosphatase 1, regulatory subunit 103
Locus 17q21, 31
Discovery year 2001-06-22
GenBank acession J03778
Entrez gene record 4137
Pubmed identfication 7936241 3131773
RefSeq identity NM_016835
Classification Protein phosphatase 1 regulatory subunits
Havana BLAST/BLAT OTTHUMG00000168833
Locus Specific Databases Alzheimer Disease &, Frontotemporal Dementia Mutation Database ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_660

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