Name : Tau (Thr548) Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :281
SKU : GEN3720943751
| Long name | Tau (Thr548) Primary Polyclonal Antibody |
| Also known as | Tau (Thr548) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Tau Thr548 |
| Specificity | This is a highly specific antibody against Tau Thr548 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr548 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 210-250/441 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human Tau around the phosphorylation site of Thr548 [VR(p-T)PP] |
| Gene ID number | 4137 |
| Swiss Prot | P10636 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, suggesting that tau functions as a linker protein between both, Promotes microtubule assembly and stability |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DDPAC, FTDP-17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, PPND, PPP1R13, Paired helical filament-tau, TAU |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Tau (Thr548) |
| Short name | Tau (Thr548) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Taurine (Thr548) (Antibody to) |
| Alternative technique | antibodies |