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Tau (Thr548) Antibody, Biotin Conjugated

Tau (Thr548) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, Tau (Thr548) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTau Thr548
SpecificityThis is a highly specific antibody against Tau Thr548
ModificationPhosphorylation
Modification siteThr548
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range210-250/441
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human Tau around the phosphorylation site of Thr548 [VR(p-T)PP]
Gene ID number4137
Swiss ProtP10636
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome, The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization, and might be involved in the establishment and maintenance of neuronal polarity, suggesting that tau functions as a linker protein between both, Promotes microtubule assembly and stability
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DDPAC, FTDP-17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, PPND, PPP1R13, Paired helical filament-tau, TAU
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTau (Thr548) Conjugated
Short name Conjugated, Tau (Thr548) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Taurine (Thr548) (Antibody to)
Alternative techniqueantibodies

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