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TAZ Antibody

TAZ Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTAZ Primary Polyclonal Antibody
Also known asTAZ PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTAZ
SpecificityThis is a highly specific antibody against TAZ
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range15-70/400
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TAZ
Gene ID number25937
Swiss ProtQ9GZV5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Regulates embryonic stem-cell self-renewal, Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex, The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, promotes cell proliferation and epithelial-mesenchymal transition, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ, Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Transcriptional coactivator with PDZ-binding motif, WW domain-containing transcription regulator protein 1, WWTR1, TAZ
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTAZ
Short nameTAZ Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTAZ (Antibody to)
Alternative techniqueantibodies
Identity 24042
Gene WWTR1
Long gene name WW domain containing transcription regulator 1
Synonyms TAZ DKFZp586I1419
Locus 3q25, 1
Discovery year 2004-12-03
GenBank acession AK022036
Entrez gene record 25937
Pubmed identfication 11118213 15096513
RefSeq identity NM_015472
Havana BLAST/BLAT OTTHUMG00000159614

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