Name : TAZ Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4078423656
| Long name | ALEXA FLUOR 555 Conjugated, TAZ Polyclonal Antibody |
| Also known as | Anti-TAZ PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TAZ |
| Specificity | This is a highly specific antibody against TAZ |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 15-70/400 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TAZ |
| Gene ID Number | 25937 |
| Swiss Prot | Q9GZV5 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Regulates embryonic stem-cell self-renewal, Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex, The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, promotes cell proliferation and epithelial-mesenchymal transition, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ, Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | TAZ DKFZp586I1419 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | TAZ |
| Short name | TAZ Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, TAZ (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24042 |
| Gene | WWTR1 |
| Long gene name | WW domain containing transcription regulator 1 |
| Locus | 3q25, 1 |
| Discovery year | 2004-12-03 |
| GenBank acession | AK022036 |
| Entrez gene record | 25937 |
| Pubmed identfication | 11118213 15096513 |
| RefSeq identity | NM_015472 |
| Havana BLAST/BLAT | OTTHUMG00000159614 |