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TAZ Antibody, Biotin Conjugated

TAZ Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, TAZ Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTAZ
SpecificityThis is a highly specific antibody against TAZ
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range15-70/400
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human TAZ
Gene ID number25937
Swiss ProtQ9GZV5
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Regulates embryonic stem-cell self-renewal, Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex, The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, promotes cell proliferation and epithelial-mesenchymal transition, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ, Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TAZ DKFZp586I1419
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTAZ Conjugated
Short name Conjugated, TAZ Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TAZ (Antibody to)
Alternative techniqueantibodies
Identity 24042
Gene WWTR1
Long gene name WW domain containing transcription regulator 1
Locus 3q25, 1
Discovery year 2004-12-03
GenBank acession AK022036
Entrez gene record 25937
Pubmed identfication 11118213 15096513
RefSeq identity NM_015472
Havana BLAST/BLAT OTTHUMG00000159614

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