Name : TBCE Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN9721572756
| Long name | ALEXA FLUOR 488 Conjugated, TBCE Polyclonal Antibody |
| Also known as | Anti-TBCE PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TBCE |
| Specificity | This is a highly specific antibody against TBCE |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TBCE |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Biosynthesis of functional microtubules involve the participation of several chaperones, D (TBCD), E (TBCE) and C (TBCC), KCS, KCS1 or pac2, Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1, TBCE (tubulin folding cofactor E), TBCE associates with microtubules and proteasomes, TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network, also known as HRD, alternatively named TCP, and protects against misfolded protein stress, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats, termed Tubulin folding cofactors A (TBCA), that act on folding intermediates downstream of the cytosolic chaperon, the primary component of the cytoskeletal network, Microtubules |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | KCS1 pac2 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the TBCE Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | TBCE |
| Short name | TBCE Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, TBCE (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11582 |
| Gene | TBCE |
| Long gene name | tubulin folding cofactor E |
| Synonyms gene | KCS HRD |
| Synonyms gene name | and dysmorphism , growth and mental retardation, tubulin-specific chaperone e Kenny-Caffey syndrome hypoparathyroidism |
| Locus | 1q42, 3 |
| Discovery year | 1998-07-31 |
| GenBank acession | U61232 |
| Entrez gene record | 6905 |
| Pubmed identfication | 8706133 9806825 12389028 |
| RefSeq identity | NM_003193 |
| Havana BLAST/BLAT | OTTHUMG00000039987 |