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TBCE Antibody, Biotin Conjugated

TBCE Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, TBCE Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTBCE
SpecificityThis is a highly specific antibody against TBCE
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human TBCE
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Biosynthesis of functional microtubules involve the participation of several chaperones, D (TBCD), E (TBCE) and C (TBCC), KCS, KCS1 or pac2, Mutations in the gene encoding TBCE are the cause of hypoparathyroidism-retardation-dysmorphism syndrome and Kenny-Caffey syndrome type 1, TBCE (tubulin folding cofactor E), TBCE associates with microtubules and proteasomes, TBCE is involved in the second step of the Tubulin folding pathway and is implicated in the maintenance of the neuronal microtubule network, also known as HRD, alternatively named TCP, and protects against misfolded protein stress, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers, is a 527 amino acid cytoplasmic protein containing one CAP-Gly domain and seven LRR (leucine-rich) repeats, termed Tubulin folding cofactors A (TBCA), that act on folding intermediates downstream of the cytosolic chaperon, the primary component of the cytoskeletal network, Microtubules
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms KCS1 pac2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTBCE Conjugated
Short name Conjugated, TBCE Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TBCE (Antibody to)
Alternative techniqueantibodies
Identity 11582
Gene TBCE
Long gene name tubulin folding cofactor E
Synonyms gene KCS HRD
Synonyms gene name and dysmorphism , growth and mental retardation, tubulin-specific chaperone e Kenny-Caffey syndrome hypoparathyroidism
Locus 1q42, 3
Discovery year 1998-07-31
GenBank acession U61232
Entrez gene record 6905
Pubmed identfication 8706133 9806825 12389028
RefSeq identity NM_003193
Havana BLAST/BLAT OTTHUMG00000039987

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