| Long name | Cy5 Conjugated, TBX1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TBX1 |
| Specificity | This is a highly specific antibody against TBX1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human TBX1 |
| Gene ID number | 6899 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CTHM consist of cardiac outflow tract defects, DGS is characterized by the association of several malformations: hypoplastic thymus and parathyroid glands, Is required for normal development of the pharyngeal arch arteries, It is now accepted that these two syndromes represent two forms of clinical expression of the same entity manifesting at different stages of life, VCFS is marked by the association of congenital conotruncal heart defects, and a subtle but characteristic facial dysmorphology, and aortic arch anomalies, cleft palate or velar insufficiency, congenital conotruncal cardiopathy, double-outlet right ventricle, facial dysmorpholgy and learning difficulties, pulmonary atresia, such as tetralogy of Fallot, truncus arteriosus communis, Defects in TBX1 are a cause of DiGeorge syndrome (DGS) , Defects in TBX1 are a cause of conotruncal heart malformations (CTHM), Defects in TBX1 are a cause of velocardiofacial syndrome (VCFS) , Involvement in disease:Haploinsufficiency of the TBX1 gene is responsible for most of the physical malformations present in DiGeorge syndrome (DGS) and velocardiofacial syndrome (VCFS) , Probable transcriptional regulator involved in developmental processes |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | CATCH22 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TBX1 Conjugated |
| Short name | Conjugated, TBX1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, T-box 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | CAFS and CATCH22 and CTHM and DGCR and DGS and DORV and TBX1C and TGA and VCF and VCFS, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0007368 and determination of left/right symmetry and biological process this GO :0007389 and pattern specification process and biological process this GO :0007498 and mesoderm development and biological process this GO :0007507 and heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0021644 and vagus nerve morphogenesis and biological process this GO :0030855 and epithelial cell differentiation and biological process this GO :0030878 and thyroid gland development and biological process this GO :0035176 and social behavior and biological process this GO :0035909 and aorta morphogenesis and biological process this GO :0042471 and ear morphogenesis and biological process this GO :0042472 and inner ear morphogenesis and biological process this GO :0042473 and outer ear morphogenesis and biological process this GO :0042474 and middle ear morphogenesis and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042693 and muscle cell fate commitment and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043587 and tongue morphogenesis and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048514 and blood vessel morphogenesis and biological process this GO :0048538 and thymus development and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048701 and embryonic cranial skeleton morphogenesis and biological process this GO :0048703 and embryonic viscerocranium morphogenesis and biological process this GO :0048752 and semicircular canal morphogenesis and biological process this GO :0048844 and artery morphogenesis and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0060017 and parathyroid gland development and biological process this GO :0060023 and soft palate development and biological process this GO :0060037 and pharyngeal system development and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060415 and muscle tissue morphogenesis and biological process this GO :0060982 and coronary artery morphogenesis and biological process this GO :0070166 and enamel mineralization and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071600 and otic vesicle morphogenesis and biological process this GO :0072513 and positive regulation of secondary heart field cardioblast proliferation and biological process this GO :0090103 and cochlea morphogenesis and biological process this GO :0097152 and mesenchymal cell apoptotic process and biological process this GO :2000027 and regulation of organ morphogenesis and biological process this GO :2001037 and positive regulation of tongue muscle cell differentiation and biological process this GO :2001054 and negative regulation of mesenchymal cell apoptotic process and biological process, TBX1 and IDBG-1419 and ENSG00000184058 and 6899, Tbx1 and IDBG-141945 and ENSMUSG00000009097 and 21380, nuclei, protein dimerization activity, this GO :0001525 and angiogenesis and biological process this GO :0001568 and blood vessel development and biological process this GO :0001708 and cell fate specification and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0001945 and lymph vessel development and biological process this GO :0001974 and blood vessel remodeling and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003148 and outflow tract septum morphogenesis and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0043565: sequence-specific DNA binding and also this GO :0046983: protein dimerization activity, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0042803: protein homodimerization activity, this GO :0043565: sequence-specific DNA binding, this GO :0046983: protein dimerization activity, T-box 1 |
| Identity | 11592 |
| Gene | TBX1 |
| Long gene name | T-box 1 |
| Synonyms gene | VCF |
| Synonyms gene name | velocardiofacial syndrome |
| Locus | 22q11, 21 |
| Discovery year | 1997-05-15 |
| GenBank acession | AF012131 |
| Entrez gene record | 6899 |
| Pubmed identfication | 9268629 23000736 |
| RefSeq identity | NM_080647 |
| Classification | T-boxes |
| Havana BLAST/BLAT | OTTHUMG00000150421 |
| Locus Specific Databases | LRG_226 |
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