| Alternative name 1 | Clone: 5G2, Mab anti-, TCF3 |
| Alternative name 2 | Clone: 5G2, Mab antibody-, TCF3 |
| Alternative name 3 | Clone: 5G2, Mab antibody-, TCF3 |
| Alternative name 4 | anti-TCF3 Clone: 5G2 |
| Alternative name 5 | TCF3 Clone: 5G2 |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | Monoclonal 5G2, TCF3 |
| Short name | Mouse Monoclonal antibody- Clone: 5G2, TCF3 |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Mouses, Mouse |
| Alternative name | Mouse monoclonal (Antibody to)-, clonality: 5G2, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) |
| Alternative technique | murine |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0030098 and lymphocyte differentiation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0035326 and enhancer binding and molecular function this GO :0042493 and response to drug and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048468 and cell development and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0050821 and protein stabilization and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070644 and vitamin D response element binding and molecular function this GO :0070888 and E-box binding and molecular function this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, E-box binding, TCF3 and IDBG-14881 and ENSG00000071564 and 6929, TCF3 and IDBG-645672 and ENSBTAG00000008695 and 530616, Tcf3 and IDBG-174161 and ENSMUSG00000020167 and 21423, bHLHb21 and E2A and E47 and ITF1 and TCF-3 and VDIR, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000788 and nuclear nucleosome and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001779 and natural killer cell differentiation and biological process this GO :0002326 and B cell lineage commitment and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding and also this GO :0035326: enhancer binding and also this GO :0042803: protein homodimerization activity and also this GO :0043425: bHLH transcription factor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046982: protein heterodimerization activity and also this GO :0046983: protein dimerization activity and also this GO :0070491: repressing transcription factor binding and also this GO :0070644: vitamin D response element binding and also this GO :0070888: E-box binding, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, this GO :0035326: enhancer binding, this GO :0042803: protein homodimerization activity, this GO :0043425: bHLH transcription factor binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046982: protein heterodimerization activity, this GO :0046983: protein dimerization activity, this GO :0070491: repressing transcription factor binding, this GO :0070644: vitamin D response element binding, this GO :0070888: E-box binding, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) |
| Identity | 11640 |
| Gene | TCF7L1 |
| Long gene name | transcription factor 7 like 1 |
| Synonyms gene | TCF3 |
| Synonyms gene name | HMG-box) , transcription factor 7-like 1 (T-cell specific |
| Locus | 2p11, 2 |
| Discovery year | 1998-01-20 |
| GenBank acession | X62870 |
| Entrez gene record | 83439 |
| Pubmed identfication | 1741298 11085512 |
| RefSeq identity | NM_031283 |
| Havana BLAST/BLAT | OTTHUMG00000130026 |
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