| Long name | TCF3(Thr355) Primary Polyclonal Antibody |
| Also known as | TCF3(Thr355) PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TCF3 Thr355 |
| Specificity | This is a highly specific antibody against TCF3 Thr355 |
| Modification(s) | Phosphorylation |
| Modification site(s) | Thr355 |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Intracellular |
| Source | KLH conjugated synthetic phosphopeptide derived from human TCF3 around the phosphorylation site of Thr355 |
| Gene ID number | 6929 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer, Dimers bind DNA on E-box motifs: 5'-CANNTG-3', like muscle or early B-cell differentiation, Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | Class B basic helix-loop-helix protein 21, E12, E2A, E2A immunoglobulin enhancer binding factors E12/E47, E47, Helix loop helix protein HE47, ITF1, Immunoglobulin enhancer-binding factor E12/E47, Kappa E2 binding factor, Kappa-E2-binding factor, MGC129647, MGC129648, Negative vitamin D response element binding protein, TCF-3, TCF3, TFE2, TFE2_MOUSE, Transcription factor E2-alpha, Transcription factor ITF-1, VDIR, VDR interacting repressor, bHLHb21, immunoglobulin transcription factor 1, p-E47phospho T355, p-TCF3phospho T355, transcription factor 3, TCF3/E2Aphospho T355 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TCF3(Thr355) |
| Short name | TCF3(Thr355) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)(Thr355) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0030098 and lymphocyte differentiation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0035326 and enhancer binding and molecular function this GO :0042493 and response to drug and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048468 and cell development and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0050821 and protein stabilization and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070644 and vitamin D response element binding and molecular function this GO :0070888 and E-box binding and molecular function this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, E-box binding, TCF3 and IDBG-14881 and ENSG00000071564 and 6929, TCF3 and IDBG-645672 and ENSBTAG00000008695 and 530616, Tcf3 and IDBG-174161 and ENSMUSG00000020167 and 21423, bHLHb21 and E2A and E47 and ITF1 and TCF-3 and VDIR, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000788 and nuclear nucleosome and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001779 and natural killer cell differentiation and biological process this GO :0002326 and B cell lineage commitment and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding and also this GO :0035326: enhancer binding and also this GO :0042803: protein homodimerization activity and also this GO :0043425: bHLH transcription factor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046982: protein heterodimerization activity and also this GO :0046983: protein dimerization activity and also this GO :0070491: repressing transcription factor binding and also this GO :0070644: vitamin D response element binding and also this GO :0070888: E-box binding, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, this GO :0035326: enhancer binding, this GO :0042803: protein homodimerization activity, this GO :0043425: bHLH transcription factor binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046982: protein heterodimerization activity, this GO :0046983: protein dimerization activity, this GO :0070491: repressing transcription factor binding, this GO :0070644: vitamin D response element binding, this GO :0070888: E-box binding, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) |
| Identity | 11640 |
| Gene | TCF7L1 |
| Long gene name | transcription factor 7 like 1 |
| Synonyms gene | TCF3 |
| Synonyms gene name | HMG-box) , transcription factor 7-like 1 (T-cell specific |
| Locus | 2p11, 2 |
| Discovery year | 1998-01-20 |
| GenBank acession | X62870 |
| Entrez gene record | 83439 |
| Pubmed identfication | 1741298 11085512 |
| RefSeq identity | NM_031283 |
| Havana BLAST/BLAT | OTTHUMG00000130026 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue