| Long name | ALEXA FLUOR 647 Conjugated, TCF3(Thr355) Polyclonal Antibody |
| Also known as | Anti-TCF3 Thr355 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TCF3 Thr355 |
| Specificity | This is a highly specific antibody against TCF3 Thr355 |
| Modification | Phosphorylation |
| Modification Site | Thr355 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Intracellular |
| Source | KLH conjugated synthetic phosphopeptide derived from human TCF3 around the phosphorylation site of Thr355 |
| Gene ID Number | 6929 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer, Dimers bind DNA on E-box motifs: 5'-CANNTG-3', like muscle or early B-cell differentiation, Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the TCF3(Thr355) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | TCF3(Thr355) |
| Short name | TCF3(Thr355) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)(Thr355) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0010628 and positive regulation of gene expression and biological process this GO :0030098 and lymphocyte differentiation and biological process this GO :0030183 and B cell differentiation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031435 and mitogen-activated protein kinase kinase kinase binding and molecular function this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033152 and immunoglobulin V(D)J recombination and biological process this GO :0035326 and enhancer binding and molecular function this GO :0042493 and response to drug and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0043425 and bHLH transcription factor binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0043966 and histone H3 acetylation and biological process this GO :0043967 and histone H4 acetylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048468 and cell development and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0050821 and protein stabilization and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070644 and vitamin D response element binding and molecular function this GO :0070888 and E-box binding and molecular function this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process, E-box binding, TCF3 and IDBG-14881 and ENSG00000071564 and 6929, TCF3 and IDBG-645672 and ENSBTAG00000008695 and 530616, Tcf3 and IDBG-174161 and ENSMUSG00000020167 and 21423, bHLHb21 and E2A and E47 and ITF1 and TCF-3 and VDIR, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000788 and nuclear nucleosome and cellular component this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001779 and natural killer cell differentiation and biological process this GO :0002326 and B cell lineage commitment and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003713: transcription coactivator activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0031435: mitogen-activated protein kinase kinase kinase binding and also this GO :0035326: enhancer binding and also this GO :0042803: protein homodimerization activity and also this GO :0043425: bHLH transcription factor binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046982: protein heterodimerization activity and also this GO :0046983: protein dimerization activity and also this GO :0070491: repressing transcription factor binding and also this GO :0070644: vitamin D response element binding and also this GO :0070888: E-box binding, this GO :0001078: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003713: transcription coactivator activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0031435: mitogen-activated protein kinase kinase kinase binding, this GO :0035326: enhancer binding, this GO :0042803: protein homodimerization activity, this GO :0043425: bHLH transcription factor binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046982: protein heterodimerization activity, this GO :0046983: protein dimerization activity, this GO :0070491: repressing transcription factor binding, this GO :0070644: vitamin D response element binding, this GO :0070888: E-box binding, transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) |
| Identity | 11640 |
| Gene | TCF7L1 |
| Long gene name | transcription factor 7 like 1 |
| Synonyms gene | TCF3 |
| Synonyms gene name | HMG-box) , transcription factor 7-like 1 (T-cell specific |
| Locus | 2p11, 2 |
| Discovery year | 1998-01-20 |
| GenBank acession | X62870 |
| Entrez gene record | 83439 |
| Pubmed identfication | 1741298 11085512 |
| RefSeq identity | NM_031283 |
| Havana BLAST/BLAT | OTTHUMG00000130026 |
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