Name : TEM1/CD248 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5182469510
| Long name | TEM1/CD248 Primary Polyclonal Antibody |
| Also known as | TEM1/CD248 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TEM1/CD248 |
| Specificity | This is a highly specific antibody against TEM1/CD248 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 280-320/757 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TEM 1 |
| Gene ID number | 57124 |
| Swiss Prot | Q9HCU0 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is believed to play a role in tumor angiogenesis, It is expressed in stromal fibroblasts, TEM1 is being investigated as a potential target for cancer treatment, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing, The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD164L1, CD248, Endosialin, Tumor endothelial marker 1, TEM1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TEM1/CD248 |
| Short name | TEM1/CD248 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | endosialin (Antibody to), TEM1/CD248 molecule |
| Alternative technique | antibodies |
| Alternative to gene target | CD248 and IDBG-58835 and ENSG00000174807 and 57124, CD248 and IDBG-644374 and ENSBTAG00000044073 and 520070, Cd248 and IDBG-130731 and ENSMUSG00000056481 and 70445, Extracellular, endosialin, extracellular matrix binding, this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008150 and biological process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0048535 and lymph node development and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0060033 and anatomical structure regression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, this GO :0050840: extracellular matrix binding, CD248 molecule |
| Identity | 18219 |
| Gene | CD248 |
| Long gene name | CD248 molecule |
| Synonyms gene | CD164L1 |
| Synonyms gene name | CD164 sialomucin-like 1 CD248 antigen, endosialin , endosialin CD248 molecule |
| Synonyms | TEM1 |
| Synonyms name | endosialin tumor endothelial marker 1 |
| Locus | 11q13, 2 |
| Discovery year | 2003-08-27 |
| GenBank acession | AF279142 |
| Entrez gene record | 57124 |
| Pubmed identfication | 10947988 11084048 |
| RefSeq identity | NM_020404 |
| Classification | CD molecules C-type lectin domain containing |
| Havana BLAST/BLAT | OTTHUMG00000167073 |