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TEM1/CD248 Antibody, Biotin Conjugated

TEM1/CD248 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, TEM1/CD248 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTEM1/CD248
SpecificityThis is a highly specific antibody against TEM1/CD248
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range280-320/757
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human TEM 1
Gene ID number57124
Swiss ProtQ9HCU0
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It is believed to play a role in tumor angiogenesis, It is expressed in stromal fibroblasts, TEM1 is being investigated as a potential target for cancer treatment, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing, The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TEM1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTEM1/CD248 Conjugated
Short name Conjugated, TEM1/CD248 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, endosialin (Antibody to), TEM1/CD248 molecule
Alternative techniqueantibodies
Alternative to gene target CD248 and IDBG-58835 and ENSG00000174807 and 57124, CD248 and IDBG-644374 and ENSBTAG00000044073 and 520070, Cd248 and IDBG-130731 and ENSMUSG00000056481 and 70445, Extracellular, endosialin, extracellular matrix binding, this GO :0003674 and molecular function and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0008150 and biological process and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0048535 and lymph node development and biological process this GO :0050840 and extracellular matrix binding and molecular function this GO :0060033 and anatomical structure regression and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000353 and positive regulation of endothelial cell apoptotic process and biological process, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding and also this GO :0050840: extracellular matrix binding, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, this GO :0050840: extracellular matrix binding, CD248 molecule
Identity 18219
Gene CD248
Long gene name CD248 molecule
Synonyms gene CD164L1
Synonyms gene name CD164 sialomucin-like 1 CD248 antigen, endosialin , endosialin CD248 molecule
Synonyms name endosialin tumor endothelial marker 1
Locus 11q13, 2
Discovery year 2003-08-27
GenBank acession AF279142
Entrez gene record 57124
Pubmed identfication 10947988 11084048
RefSeq identity NM_020404
Classification CD molecules C-type lectin domain containing
Havana BLAST/BLAT OTTHUMG00000167073

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