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TERT Antibody (phospho-Y707)

TERT Antibody (phospho-Y707) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTERT (phospho-Y707)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications DB, ELISA, IF
Recommended dilutionsDot blot: 1:500, Immunofluorescence: 1:10-1:50
NotesTitration of the phospho-TERT antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-TERT antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O14746
PurityAntigen affinity
Description Deregulation of telomerase expression in somatic cells may be involved in oncogenesis, Studies in mouse suggest that telomerase also participates in chromosomal repair, Telomerase expression plays a role in cellular senescence, The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres, since de novo synthesis of telomere repeats may occur at double-stranded breaks, Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG
ImmunogenThis phospho-TERT antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY707 of human TERT
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-TERT antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTERT (phospho-Y707)
Short nameTERT Antibody (phospho-Y707)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nametelomerase reverse transcriptase (Antibody to) (phosphorilated-Y707)
Alternative techniqueantibodies
Alternative to gene target BT, CMM9 and DKCA2 and DKCB4 and EST2 and hEST2 and hTRT and PFBMFT1 and TCS1 and TP2 and TRT, TERT and IDBG-10998 and ENSG00000164362 and 7015, Tert and IDBG-165912 and ENSMUSG00000021611 and 21752, nuclei, telomeric RNA binding, telomeric region and cellular component this GO :0000783 and nuclear telomere cap complex and cellular component this GO :0003720 and telomerase activity and molecular function this GO :0003721 and telomeric template RNA reverse transcriptase activity and molecular function this GO :0003964 and RNA-directed DNA polymerase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005697 and telomerase holoenzyme complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007004 and telomere maintenance via telomerase and biological process this GO :0016605 and PML body and cellular component this GO :0022616 and DNA strand elongation and biological process this GO :0032203 and telomere formation via telomerase and biological process this GO :0042162 and telomeric DNA binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0046872 and metal ion binding and molecular function this GO :0070034 and telomeric RNA binding and molecular function this GO :0090399 and replicative senescence and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0000723 and telomere maintenance and biological process this GO :0000781 and chromosome, this GO :0003720: telomerase activity, this GO :0003720: telomerase activity and also this GO :0003721: telomeric template RNA reverse transcriptase activity and also this GO :0003964: RNA-directed DNA polymerase activity and also this GO :0005515: protein binding and also this GO :0042162: telomeric DNA binding and also this GO :0042803: protein homodimerization activity and also this GO :0046872: metal ion binding and also this GO :0070034: telomeric RNA binding, this GO :0003721: telomeric template RNA reverse transcriptase activity, this GO :0003964: RNA-directed DNA polymerase activity, this GO :0005515: protein binding, this GO :0042162: telomeric DNA binding, this GO :0042803: protein homodimerization activity, this GO :0046872: metal ion binding, this GO :0070034: telomeric RNA binding, 60929 and IDBG-632169 and ENSBTAG00000012567 and 518884, telomerase reverse transcriptase
Identity 11730
Gene TERT
Long gene name telomerase reverse transcriptase
Synonyms TRT TP2 TCS1 hEST2 EST2
Locus 5p15, 33
Discovery year 1998-01-21
GenBank acession AF015950
Pubmed identfication 9252327
Havana BLAST/BLAT OTTHUMG00000090357
Locus Specific Databases LRG_343

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