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TFE3 Antibody

TFE3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTFE3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IF, WB
Recommended dilutionsImmunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the TFE3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TFE3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P19532
PurityAntigen affinity
Description NonO (p54nrb)-TFE3 and ASPL-TFE3, PSF-TFE3, RCC17-TFE3, SMAD3, TFE3, TFEB and TFEC, The TEF3 protein encoded by this gene activates transcription through binding to the muE3 motif of the immunoglobulin heavy-chain enhancer, The TEF3 protein interacts with transcription regulators such as E2F3, The TFE3 protein also activates hepatic IRS-2 gene, The TFEC protein forms heterodimers with the TEF3 protein and inhibits TFE3-dependent transcription activation, This gene is also involved in chromosomal translocations, and LEF-1, and induces hexokinase II (HK2) and insulin-induced gene 1 (INSIG1), and is involved in TGF-beta-induced transcription, and osteoclast and macrophage differentiation, it participates in insulin signaling and could be a therapeutic target for diabetes, playing important roles in cell growth, proliferation, resulting in different fusion gene products in papillary renal cell carcinomas and alveolar soft part sarcomas, such as PRCC-TFE3, The microphthalmia transcription factor/transcription factor E (MITF-TFE) family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors includes four family members: MITF
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this TFE3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TFE3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTFE3
Short nameTFE3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTFE3 (Antibody to)
Alternative techniqueantibodies
Identity 11752
Gene TFE3
Long gene name transcription factor binding to IGHM enhancer 3
Synonyms TFEA bHLHe33
Synonyms name transcription factor E family member A
Locus Xp11, 23
Discovery year 1990-10-16
GenBank acession X96717
Entrez gene record 7030
Pubmed identfication 1672758 1685140
RefSeq identity NM_006521
Classification Basic helix-loop-helix proteins
Havana BLAST/BLAT OTTHUMG00000022690
Locus Specific Databases Mental Retardation database

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