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TGF Beta 1+2+3 Antibody, Biotin Conjugated

TGF Beta 1+2+3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, TGF Beta 1+2+3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTGF Beta 1+2+3
Specificity This antibody will preferentially react with TGFB1, but will also detect TGFB2 (93%) and TGFB3 (86%) based upon sequence similarity, This is a highly specific antibody against TGF Beta 1+2+3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range280-330/390
Subcellular location Secreted, Extracellular
SourceKLH conjugated synthetic peptide derived from human TGF Beta 1
Gene ID number7040
Swiss ProtP01137
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background At high concentrations, At low concentrations in concert with IL-6 and IL-21, Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner, It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, It positively and negatively regulates many other growth factors, Many cells synthesize TGFB1 and have specific receptors for it, causing chemotaxis, differentiation and other functions in many cell types, favoring Treg cell development, favoring differentiation to Th17 cells, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, leads to expression of the IL-17 and IL-23 receptors, proliferation and differentiation in committed osteoblasts, Multifunctional protein that controls proliferation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DPD1, LAP, TGF-beta-1, TGFB, TGFB1, TGFbeta, Transforming growth factor beta-1, CED
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTGF Beta 1+2+3 Conjugated
Short name Conjugated, TGF Beta 1+2+3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TGF b 1+2+3 (Antibody to)
Alternative techniqueantibodies

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