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TGF Beta R3 Antibody, FITC Conjugated

TGF Beta R3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, TGF Beta R3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTGF Beta R3
SpecificityThis is a highly specific antibody against TGF Beta R3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human TGFBR3
Gene ID number7049
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Endothelial cells undergoing epithelial mesenchymal transformation express TGF beta III receptor, In addition to type I TGF beta receptor (TGFBR1) and type II (TFGBR2), Inhibin forms crosslinked complexes with both recombinant and endogenously expressed TGF beta III receptor and ActRII, It is a glycoprotein that binds TGF beta and exists in both a membrane bound and a soluble form, It may serve as a receptor accessory molecule in both the TGF beta and fibroblast growth factor systems, Misexpression of TGF beta III receptor in nontransforming ventricular endothelial cells conferrs transformation in response to TGFB2, TGF beta III receptor, TGF beta III receptor binds inhibin with high affinity and enhances binding in cells coexpressing ActRII and TGF beta III receptor, TGF beta III receptor confers inhibin sensitivity to cell lines that otherwise respond poorly to this hormone, TGF beta III receptor lacks a recognizable signaling domain and has no clearly defined role in TGF beta signaling, TGFB2, The diverse effects of TGF beta are mediated by the TGF beta receptors and cell surface binding proteins, There are 3 forms encoded by separate genes TGFB1, These results support a model where TGF beta III receptor localizes transformation in the heart and plays an essential, adhesion, and TGF beta III receptor specific antisera inhibits mesenchyme formation and migration, and TGFB3, and extracellular matrix production, can function as an inhibin coreceptor with ActRII, cell cycle progression, cellular migration, including cell differentiation, nonredundant role in TGF beta signaling, or beta glycan, type III (TGF beta III receptor) has been identified, Membrane Receptors Transforming growth factor beta is a multifunctional cytokine known to modulate several tissue development and repair processes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms BGCAN, Betaglycan, Betaglycan proteoglycan, TGF beta Receptor III, TGF beta receptor type 3, TGF beta receptor type III, TGFB R3, TGFBR 3, TGFBR3, TGFR 3, TGFR3, Transforming Growth Factor Beta Receptor III, Transforming growth factor beta receptor III betaglycan 300kDa, Beta glycan
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTGF Beta R3 Conjugated
Short name FITC Conjugated, TGF Beta R3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TGF b R3 (Antibody to)
Alternative techniqueantibodies

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