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Thioredoxin 2 Antibody

Thioredoxin 2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameThioredoxin 2 Primary Polyclonal Antibody
Also known asThioredoxin 2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenThioredoxin 2
SpecificityThis is a highly specific antibody against Thioredoxin 2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Thioredoxin 2
Gene ID number25828
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen NF-kB and AP-1, Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor, Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, The reduced Trx is a hydrogen donor for ribonucleotide reductase, The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds, Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site, Trx is also capable of removing H2O2, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins, the essential enzyme for DNA synthesis, Thioredoxins (Trx) are small
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MT-TRX, MTRX, TRX 2, TRX2, TXN 2, TXN2, Thioredoxin mitochondrial, Thioredoxin2, thioredoxin 2 precursor, mitochondrial thioredoxin
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetThioredoxin 2
Short nameThioredoxin 2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameThioredoxin 2 (Antibody to)
Alternative techniqueantibodies
Identity 16470
Gene TXNDC2
Long gene name thioredoxin domain containing 2
Synonyms gene name thioredoxin domain containing 2 (spermatozoa)
Synonyms SPTRX1
Synonyms name sperm-specific thioredoxin 1
Locus 18p11, 2 , 31-p11
Discovery year 2001-08-30
GenBank acession AF080095
Pubmed identfication 11230166 11399755
Havana BLAST/BLAT OTTHUMG00000131602

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