Name : Thioredoxin 2 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1304244696
| Long name | ALEXA FLUOR 488 Conjugated, Thioredoxin 2 Polyclonal Antibody |
| Also known as | Anti-Thioredoxin 2 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Thioredoxin 2 |
| Specificity | This is a highly specific antibody against Thioredoxin 2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Thioredoxin 2 |
| Gene ID Number | 25828 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | NF-kB and AP-1, Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor, Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, The reduced Trx is a hydrogen donor for ribonucleotide reductase, The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds, Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site, Trx is also capable of removing H2O2, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins, the essential enzyme for DNA synthesis, Thioredoxins (Trx) are small |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | SPTRX1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Thioredoxin 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Thioredoxin 2 |
| Short name | Thioredoxin 2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Thioredoxin 2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16470 |
| Gene | TXNDC2 |
| Long gene name | thioredoxin domain containing 2 |
| Synonyms gene name | thioredoxin domain containing 2 (spermatozoa) |
| Synonyms name | sperm-specific thioredoxin 1 |
| Locus | 18p11, 2 , 31-p11 |
| Discovery year | 2001-08-30 |
| GenBank acession | AF080095 |
| Pubmed identfication | 11230166 11399755 |
| Havana BLAST/BLAT | OTTHUMG00000131602 |