Filters

Thioredoxin Antibody (TRX)

Thioredoxin Antibody (TRX) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenThioredoxin (TRX)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the Thioredoxin antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis Thioredoxin antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P10599
PurityPurified
Description NF-kB and AP-1, Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor, Specific protein disulfide targets for reduction by Trx include protein disulfide _x0013_isomerase(PDI) and a number of transcription factors such as p53, The reduced Trx is a hydrogen donor for ribonucleotide reductase, The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds, Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins, the essential enzyme for DNA synthesis, Thioredoxins (Trx) are small, Trx is also capable of removing H2O2
ImmunogenA portion of amino acids 1-30 from the human protein was used as the immunogen for this Thioredoxin antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Thioredoxin antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetThioredoxin (TRX)
Short nameThioredoxin Antibody (TRX)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameThioredoxin (Antibody to) (TRX)
Alternative techniqueantibodies
Identity 12435
Gene TXN
Long gene name thioredoxin
Synonyms TRX
Locus 9q31, 3
Discovery year 1990-02-05
GenBank acession X77584
Entrez gene record 7295
Havana BLAST/BLAT OTTHUMG00000020480

Similar products

Subscribe to our Newsletter