Name : THOC2 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2425006003
| Long name | ALEXA FLUOR 647 Conjugated, THOC2 Polyclonal Antibody |
| Also known as | Anti-THOC2 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | THOC2 |
| Specificity | This is a highly specific antibody against THOC2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 130-180/1593 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human THOC2 |
| Gene ID Number | 57187 |
| Swiss Prot | Q8NI27 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, Required for NXF1 localization to the nuclear rim, THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains, TREX is recruited to spliced mRNAs by a transcription-independent mechanism, The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway, processing and nuclear export, Required for efficient export of polyadenylated RNA and spliced mRNA |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | THO2 dJ506G2, 1 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the THOC2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | THOC2 |
| Short name | THOC2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, THOC2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19073 |
| Gene | THOC2 |
| Long gene name | THO complex 2 |
| Synonyms gene | CXorf3 MRX12 MRX35 |
| Synonyms gene name | X-linked 12 mental retardation, X-linked 35 , chromosome X open reading frame 3 mental retardation |
| Locus | Xq25 |
| Discovery year | 2002-12-09 |
| GenBank acession | AF441770 |
| Entrez gene record | 57187 |
| Pubmed identfication | 11979277 15998806 26166480 |
| Classification | X-linked mental retardation THO complex |
| Havana BLAST/BLAT | OTTHUMG00000022334 |
| Locus Specific Databases | Mental Retardation database |