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THOC2 Antibody, Biotin Conjugated

THOC2 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, THOC2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTHOC2
SpecificityThis is a highly specific antibody against THOC2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range130-180/1593
Subcellular locationNucleus
SourceKLH conjugated synthetic peptide derived from human THOC2
Gene ID number57187
Swiss ProtQ8NI27
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, Required for NXF1 localization to the nuclear rim, THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains, TREX is recruited to spliced mRNAs by a transcription-independent mechanism, The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway, processing and nuclear export, Required for efficient export of polyadenylated RNA and spliced mRNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms THO2 dJ506G2, 1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTHOC2 Conjugated
Short name Conjugated, THOC2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, THOC2 (Antibody to)
Alternative techniqueantibodies
Identity 19073
Gene THOC2
Long gene name THO complex 2
Synonyms gene CXorf3 MRX12 MRX35
Synonyms gene name X-linked 12 mental retardation, X-linked 35 , chromosome X open reading frame 3 mental retardation
Locus Xq25
Discovery year 2002-12-09
GenBank acession AF441770
Entrez gene record 57187
Pubmed identfication 11979277 15998806 26166480
Classification X-linked mental retardation THO complex
Havana BLAST/BLAT OTTHUMG00000022334
Locus Specific Databases Mental Retardation database

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