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TIE2 (Tyr1102) Antibody, Biotin Conjugated

TIE2 (Tyr1102) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, TIE2 (Tyr1102) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTIE2 Tyr1102
SpecificityThis is a highly specific antibody against TIE2 Tyr1102
ModificationPhosphorylation
Modification siteTyr1102
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1102
Gene ID number7010
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms TIE2 TIE-2 VMCM1 CD202b
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTIE2 (Tyr1102) Conjugated
Short name Conjugated, TIE2 (Tyr1102) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, TIE2 (Tyr1102) (Antibody to)
Alternative techniqueantibodies
Identity 11724
Gene TEK
Long gene name TEK receptor tyrosine kinase
Synonyms gene VMCM
Synonyms gene name endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations
Locus 9p21, 2
Discovery year 1994-05-24
GenBank acession L06139
Entrez gene record 7010
Pubmed identfication 1312667 7833915
Classification Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000019712

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