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TIE2 (Tyr1108) Antibody

TIE2 (Tyr1108) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTIE2 (Tyr1108) Primary Polyclonal Antibody
Also known asTIE2 (Tyr1108) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTIE2 Tyr1108
SpecificityThis is a highly specific antibody against TIE2 Tyr1108
Modification(s)Phosphorylation
Modification site(s)Tyr1108
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1108
Gene ID number7010
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Angiopoietin-1 receptor, CD202b, CD202b antigen, Endothelial tyrosine kinase, Endothelium specic receptor tyrosine kinase 2, Hyk, TEK tyrosine kinase endothelial, TIE 2, TIE2_HUMAN, Tek, Tunica interna endothelial cell kinase, Tyrosine kinase with Ig and EGF homology domains 2, Tyrosine protein kinase receptor TEK, Tyrosine protein kinase receptor TIE 2, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, VMCM, VMCM 1, VMCM1, Venous malformations multiple cutaneous and mucosal, endothelial, hTIE 2, hTIE2, hTIE2, p140 TEK, p140 TEK, tek tyrosine kinase, tek tyrosine kinase, p-TIE2 phospho Y1108
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTIE2 (Tyr1108)
Short nameTIE2 (Tyr1108) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTIE2 (Tyr1108) (Antibody to)
Alternative techniqueantibodies
Identity 11724
Gene TEK
Long gene name TEK receptor tyrosine kinase
Synonyms gene VMCM
Synonyms gene name endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations
Synonyms TIE2 TIE-2 VMCM1 CD202b
Locus 9p21, 2
Discovery year 1994-05-24
GenBank acession L06139
Entrez gene record 7010
Pubmed identfication 1312667 7833915
Classification Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000019712

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