Name : TIE2 (Tyr1108) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN3414739594
| Long name | ALEXA FLUOR 555 Conjugated, TIE2 (Tyr1108) Polyclonal Antibody |
| Also known as | Anti-TIE2 Tyr1108 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TIE2 Tyr1108 |
| Specificity | This is a highly specific antibody against TIE2 Tyr1108 |
| Modification | Phosphorylation |
| Modification Site | Tyr1108 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1108 |
| Gene ID Number | 7010 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | TIE2 TIE-2 VMCM1 CD202b |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | TIE2 (Tyr1108) |
| Short name | TIE2 (Tyr1108) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, TIE2 (Tyr1108) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11724 |
| Gene | TEK |
| Long gene name | TEK receptor tyrosine kinase |
| Synonyms gene | VMCM |
| Synonyms gene name | endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations |
| Locus | 9p21, 2 |
| Discovery year | 1994-05-24 |
| GenBank acession | L06139 |
| Entrez gene record | 7010 |
| Pubmed identfication | 1312667 7833915 |
| Classification | Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT | OTTHUMG00000019712 |