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TIE2 (Tyr1108) Antibody, FITC Conjugated

TIE2 (Tyr1108) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, TIE2 (Tyr1108) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTIE2 Tyr1108
SpecificityThis is a highly specific antibody against TIE2 Tyr1108
ModificationPhosphorylation
Modification siteTyr1108
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human TIE2 around the phosphorylation site of Tyr1108
Gene ID number7010
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in TEK are associated with inherited venous malformations, The ligand for the receptor is angiopoietin-1, This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats, and humans, rats, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis, TEK is closely related to the TIE receptor tyrosine kinase, The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms TIE2 TIE-2 VMCM1 CD202b
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTIE2 (Tyr1108) Conjugated
Short name FITC Conjugated, TIE2 (Tyr1108) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TIE2 (Tyr1108) (Antibody to)
Alternative techniqueantibodies
Identity 11724
Gene TEK
Long gene name TEK receptor tyrosine kinase
Synonyms gene VMCM
Synonyms gene name endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations
Locus 9p21, 2
Discovery year 1994-05-24
GenBank acession L06139
Entrez gene record 7010
Pubmed identfication 1312667 7833915
Classification Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000019712

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