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TIMM8A Antibody

TIMM8A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTIMM8A Primary Polyclonal Antibody
Also known asTIMM8A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTIMM8A
SpecificityThis is a highly specific antibody against TIMM8A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIMM8A
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in Tim proteins are implicated in several neuro-degenerative diseases, Import of nuclear-encoded precursor proteins into and across the mitochondrial inner membrane is mediated by two distinct complexes, The mitochondrial Tim protein family is comprised of a large group of evolutionarily conserved proteins that are found in most eukaryotes (1, Tim8A and Tim8B, Tim8A is highly expressed in fetal and adult brain (5), Tim8A is mutated in deafness dystonia syndrome, a novel type of disease that causes severe neurological defects, are conserved proteins of the mitochondrial intermembrane space, respectively, suggesting important roles for Tim proteins in development and health (3, the Tim23 complex and the Tim22 complex, thought to be caused by a defective mitochondrial protein transport system (5, which are organized in hetero-oligomeric complex with Tim13 (5, which differ in their substrate specificity (1), which map to human chromosomes Xq22, 1 and 11q23, 1-q23, 2, 2), 4), 6, 7), 8), The majority of mitochondrial-directed proteins are encoded by the nuclear genome and are transported to the mitochondria via regulated processes involving the mitochondrial Tom and Tim proteins (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DDP, DDP1, DFN 1, DFN1, Deafness dystonia protein 1, Deafness/dystonia peptide, MGC12262, MTS, Mitochondrial import inner membrane translocase subunit Tim8 A, TIM 8A, TIM8A, TIM8A_HUMAN, TIMM 8A, Translocase of inner mitochondrial membrane 8 homolog A, X linked deafness dystonia protein, DDP 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTIMM8A
Short nameTIMM8A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nametranslocase on inner mitochondrial membrane 8 homolog A (yeast) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Cytoplasm, DDP and DDP1 and DFN1 and MTS and TIM8, TIMM8A and IDBG-633444 and ENSBTAG00000022292 and 515109, TIMM8A and IDBG-79593 and ENSG00000126953 and 1678, metal ion binding, this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005758 and mitochondrial intermembrane space and cellular component this GO :0006626 and protein targeting to mitochondrion and biological process this GO :0007399 and nervous system development and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0072321 and chaperone-mediated protein transport and biological process, this GO :0046872: metal ion binding, this GO :0046872: metal ion binding, translocase of inner mitochondrial membrane 8 homolog A (yeast)
Identity 11817
Gene TIMM8A
Long gene name translocase of inner mitochondrial membrane 8A
Synonyms gene DFN1
Synonyms gene name translocase of inner mitochondrial membrane 8 (yeast) homolog A translocase of inner mitochondrial membrane 8 homolog A (yeast)
Synonyms DDP MTS
Locus Xq22, 1
Discovery year 1999-12-01
GenBank acession U66035
Entrez gene record 1678
Pubmed identfication 10552927 8841189
RefSeq identity NM_004085
Havana BLAST/BLAT OTTHUMG00000022028

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