TLE4 Antibody, Biotin Conjugated

TLE4 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 333

Size 0.1ml

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Long name	Biotin Conjugated, TLE4 Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	TLE4
Specificity	This is a highly specific antibody against TLE4
Modification	Unmodified
Modification site	None
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic peptide derived from human TLE4
Gene ID number	7091
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Mouse, Rat, Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Expression of the TLE genes, Groucho is a transcriptional repressor that plays a key role in neurogenesis, In early stages of cell differentiation, In later stages, Key players in the Notch pathway are the TLE genes (for transducin-like enhancer of split, TLE1, TLE1, TLE1 and TLE4 contain SP and WD40 domains, TLE1 is upregulated, TLE2, TLE2 and TLE3 have elevated expression in cervical squamous metaplasias and carcinomas, TLE2 and TLE4 are upregulated, TLE3 and TLE4, TLEs associate with chromatin in live cells and specifically with Histone H3, also designated ESG for enhancer of split groucho), and TLE2 and TLE4 are downregulated, and expression of TLE1 decreases, but not with other core histones, correlate with immature epithelial cells that are progressing toward a terminally differentiated state, particularly in the caudate nucleus, segmentation and sex determination, suggesting a role during epithelial differentiation, through which TLE1 binds AML1 to inhibit AML1-induced transactivation of the CSF1 receptor, which are human homologs of the Drosophila groucho gene, while TLE4 is most highly expressed in the brain, The Notch signaling pathway controls cellular interactions important for the specification of a variety of fates in both invertebrates and vertebrates
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	E(spI) ESG GRG4
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	TLE4 Conjugated
Short name	Conjugated, TLE4 Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, TLE4 (Antibody to)
Alternative technique	antibodies
Identity	11840
Gene	TLE4
Long gene name	transducin like enhancer of split 4
Synonyms gene name	Drosophila) , transducin-like enhancer of split 4 (E(sp1) homolog
Locus	9q21, 31
Discovery year	1993-12-20
GenBank acession	M99439
Entrez gene record	7091
Pubmed identfication	8365415
RefSeq identity	XM_212237
Classification	WD repeat domain containing
Havana BLAST/BLAT	OTTHUMG00000020072

TLE4 Antibody, Biotin Conjugated

TLE4 Antibody, Biotin Conjugated size: 0.1ml 333

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