| Long name | TLR7 Primary Polyclonal Antibody |
| Also known as | TLR7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TLR7 |
| Specificity | This is a highly specific antibody against TLR7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 500-550/1049 |
| Subcellular location | Intracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLR7 |
| Gene ID number | 51284 |
| Swiss Prot | Q9NYK1 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts via MYD88 and TRAF6, TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA, TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms, cytokine secretion and the inflammatory response (By similarity), leading to NF-kappa-B activation, Key component of innate and adaptive immunity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | TLR7, Toll-like receptor 7, UNQ248/PRO285, TLR7-like |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TLR7 |
| Short name | TLR7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | toll-like receptor 7 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Plasma membranes, TLR7 and IDBG-44230 and ENSG00000196664 and 51284, TLR7 and IDBG-639302 and ENSBTAG00000022161 and 493686, Tlr7 and IDBG-185532 and ENSMUSG00000044583 and 170743, siRNA binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008144 and drug binding and molecular function this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032009 and early pha this GO some and cellular component this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034154 and toll-like receptor 7 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035197 and siRNA binding and molecular function this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0043235 and receptor complex and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003725: double-stranded RNA binding, this GO :0003725: double-stranded RNA binding and also this GO :0003727: single-stranded RNA binding and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding and also this GO :0035197: siRNA binding, this GO :0003727: single-stranded RNA binding, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, this GO :0008144: drug binding, this GO :0035197: siRNA binding, toll-like receptor 7 |
| Identity | 15631 |
| Gene | TLR7 |
| Long gene name | toll like receptor 7 |
| Synonyms gene name | toll-like receptor 7 |
| Locus | Xp22, 2 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF240467 |
| Entrez gene record | 51284 |
| Pubmed identfication | 11022119 |
| RefSeq identity | NM_016562 |
| Classification | Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000021137 |
| Locus Specific Databases | Mental Retardation database |
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