Name : TLR8 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3381058909
| Long name | Biotin Conjugated, TLR8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TLR8 |
| Specificity | This is a highly specific antibody against TLR8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human TLR 8 |
| Gene ID number | 51311 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Acts via MYD88 and TRAF6, TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Key component of innate and adaptive immunity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | CD288 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TLR8 Conjugated |
| Short name | Conjugated, TLR8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, toll-like receptor 8 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Plasma membranes, TLR8 and IDBG-44288 and ENSG00000101916 and 51311, Tlr8 and IDBG-185523 and ENSMUSG00000040522 and 170744, drug binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0001774 and microglial cell activation and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003723 and RNA binding and molecular function this GO :0003725 and double-stranded RNA binding and molecular function this GO :0003727 and single-stranded RNA binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0008144 and drug binding and molecular function this GO :0009615 and response to virus and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016064 and immunoglobulin mediated immune response and biological process this GO :0034158 and toll-like receptor 8 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0036020 and endolysosome membrane and cellular component this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045416 and positive regulation of interleukin-8 biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0051607 and defense response to virus and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003723: RNA binding and also this GO :0003725: double-stranded RNA binding and also this GO :0003727: single-stranded RNA binding and also this GO :0004872: receptor activity and also this GO :0005515: protein binding and also this GO :0008144: drug binding, this GO :0003723: RNA binding, this GO :0003725: double-stranded RNA binding, this GO :0003727: single-stranded RNA binding, this GO :0004872: receptor activity, this GO :0005515: protein binding, this GO :0008144: drug binding, toll-like receptor 8 |
| Identity | 15632 |
| Gene | TLR8 |
| Long gene name | toll like receptor 8 |
| Synonyms gene name | toll-like receptor 8 |
| Locus | Xp22, 2 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF246971 |
| Entrez gene record | 51311 |
| Pubmed identfication | 11022119 |
| RefSeq identity | NM_016610 |
| Classification | CD molecules Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000021145 |
| Locus Specific Databases | Mental Retardation database |