| Long name | TLR9 Primary Polyclonal Antibody |
| Also known as | TLR9 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | TLR9 |
| Specificity | This is a highly specific antibody against TLR9 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 950-1000/1032 |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLR9 |
| Gene ID number | 54106 |
| Swiss Prot | Q9NR96 |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts via MYD88 and TRAF6, Controls lymphocyte response to Helicobacter infection, TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides, TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms, cytokine secretion and the inflammatory response, leading to NF-kappa-B activation, Key component of innate and adaptive immunity |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | TLR9, Toll-like receptor 9, UNQ5798/PRO19605, CD289 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | TLR9 |
| Short name | TLR9 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | toll-like receptor 9 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, TLR9 and IDBG-407857 and ENSG00000239732 and 54106, siRNA binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007252 and I-kappaB phosphorylation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0010008 and endosome membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0032009 and early pha this GO some and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032717 and negative regulation of interleukin-8 production and biological process this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032741 and positive regulation of interleukin-18 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034122 and negative regulation of toll-like receptor signaling pathway and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0035197 and siRNA binding and molecular function this GO :0036020 and endolysosome membrane and cellular component this GO :0042346 and positive regulation of NF-kappaB import into nucleus and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045078 and positive regulation of interferon-gamma biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045356 and positive regulation of interferon-alpha biosynthetic process and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process, this GO :0004888: transmembrane signaling receptor activity, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005149: interleukin-1 receptor binding and also this GO :0005515: protein binding and also this GO :0035197: siRNA binding, this GO :0005149: interleukin-1 receptor binding, this GO :0005515: protein binding, this GO :0035197: siRNA binding, toll-like receptor 9 |
| Identity | 15633 |
| Gene | TLR9 |
| Long gene name | toll like receptor 9 |
| Synonyms gene name | toll-like receptor 9 |
| Synonyms | CD289 |
| Locus | 3p21, 2 |
| Discovery year | 2001-04-27 |
| GenBank acession | AF259262 |
| Entrez gene record | 54106 |
| Pubmed identfication | 11022119 |
| Classification | CD molecules Toll like receptors |
| Havana BLAST/BLAT | OTTHUMG00000158106 |
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