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TLX2 Antibody, ALEXA FLUOR 350

TLX2 Antibody, ALEXA FLUOR 350 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 350 Conjugated, TLX2 Polyclonal Antibody
Also known asAnti-TLX2 PAb ALEXA FLUOR 350
CategoryConjugated Primary Antibodies
Conjugated with 350, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTLX2
SpecificityThis is a highly specific antibody against TLX2
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TLX2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Mutations in the gene encoding mouse Tlx2 lead to congenital anomalies closely resembling neuronal intestinal dysplasia in humans, TLX2, TLX2 is thought to play a role in this disease, The expression pattern of Tlx2, The mouse homolog, Thus, Tlx2, also known as homeobox protein Hox-11L1 (HOX11L1), and shares several critical domains, cranial and entric-nerve gangla, has been detected in dorsal-root ganglia, including an enhancer element in the promotor that is crucial for tissue-specific expression, intestine and heart of adult mice, is a 284 amino acid member of the TLX homeobox family, is highly homologous to mouse Tlx2, neural crest homeobox protein (NCX) or ENX, parasympathetic ganglia and adrenal glands in mouse embryos and in the adrenal glands, suggests that it may play a role in the proliferation or differentiation of the enteric peripheral nervous system, which is a rare condition characterized by hyperplasia of submucosal plexus with giant submucosal ganglia and increased acetylcholinesterase activity in nerve fiber around submucosal blood vessels, which is localized to the nucleus, which is restricted to tissues derived from nerual crest cells, T-cell leukemia homeobox protein 2 (TLX2)
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission343nm/442nm
Synonyms Enx Tlx2 NCX
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 350, Alexa Fluor
Gene targetTLX2
Short nameTLX2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 350
Alternative name ALEXA FLUOR 350, T-cell leukemia homeobox 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0008150 and biological process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0048484 and enteric nervous system development and biological process this GO :0050774 and negative regulation of dendrite morphogenesis and biological process, HOX11L1 and NCX, TLX2 and IDBG-57593 and ENSG00000115297 and 3196, TLX2 and IDBG-631278 and ENSBTAG00000016607 and 539041, Tlx2 and IDBG-159907 and ENSMUSG00000068327 and 21909, nuclei, sequence-specific DNA binding, this GO :0001707 and mesoderm formation and biological process this GO :0003674 and molecular function and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005575 and cellular component and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0003674: molecular_function, this GO :0003674: molecular_function and also this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0043565: sequence-specific DNA binding, this GO :0003677: DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0043565: sequence-specific DNA binding, T-cell leukemia homeobox 2
Identity 5057
Gene TLX2
Long gene name T-cell leukemia homeobox 2
Synonyms gene HOX11L1
Synonyms gene name homeo box 11-like 1 T-cell leukemia, homeobox 2
Locus 2p13, 1
Discovery year 1998-08-04
GenBank acession AJ002607
Entrez gene record 3196
Pubmed identfication 10343123
Classification NKL subclass homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000129960

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