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TMEM16C/Anoctamin 3 Antibody, FITC Conjugated

TMEM16C/Anoctamin 3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, TMEM16C/Anoctamin 3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTMEM16C/Anoctamin 3
SpecificityThis is a highly specific antibody against TMEM16C/Anoctamin 3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human TMEM16C/Anoctamin 3
Gene ID number63982
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Atm mutation leads to the disorder known as ataxia-telangiectasia, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, With approximately 135 million base pairs and 1, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, while Wilms' tumors, 400 genes, TMEM16C is a 981 amino acid multi-pass membrane protein that is encoded by a gene which maps to chromosome 11
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GENX-3947 DYT23
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTMEM16C/Anoctamin 3 Conjugated
Short name FITC Conjugated, TMEM16C/Anoctamin 3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, TMEM16C/Anoctamin 3 (Antibody to)
Alternative techniqueantibodies
Identity 14004
Gene ANO3
Long gene name anoctamin 3
Synonyms gene C11orf25 TMEM16C
Synonyms gene name chromosome 11 open reading frame 25 transmembrane protein 16C
Synonyms name transmembrane protein 16C (eight membrane-spanning domains)
Locus 11p14, 2
Discovery year 2000-11-28
GenBank acession AJ300461
Entrez gene record 63982
Pubmed identfication 12739008 15067359 23200863 24692353
RefSeq identity NM_031418
Classification Anoctamins
Havana BLAST/BLAT OTTHUMG00000166096

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