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TMEM173 Antibody

TMEM173 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTMEM173 Primary Polyclonal Antibody
Also known asTMEM173 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTMEM173
SpecificityThis is a highly specific antibody against TMEM173
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range260-310/379
Subcellular locationIntracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TMEM173
Gene ID number340061
Swiss ProtQ86WV6
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression, Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm, May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II), May be involved in translocon function, Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway, the translocon possibly being able to influence the induction of type I interferons, Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ERIS, MITA, Mediator of IRF3 activation, Mitochondrial mediator of IRF3 activation, hMITA, hSTING, Endoplasmic reticulum interferon stimulator
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTMEM173
Short nameTMEM173 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nametransmembrane protein 173 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target Plasma membranes, TMEM173 and IDBG-47893 and ENSG00000184584 and 340061, TMEM173 and IDBG-646026 and ENSBTAG00000002296 and 533661, Tmem173 and IDBG-137341 and ENSMUSG00000024349 and 72512, cyclic-GMP-AMP binding, this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0005515 and protein binding and molecular function this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032092 and positive regulation of protein binding and biological process this GO :0032479 and regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032608 and interferon-beta production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019901: protein kinase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0035438: cyclic-di-GMP binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0061507: cyclic-GMP-AMP binding, this GO :0008134: transcription factor binding, this GO :0019901: protein kinase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0035438: cyclic-di-GMP binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0061507: cyclic-GMP-AMP binding, translocation and biological process this GO :0035438 and cyclic-di-GMP binding and molecular function this GO :0035458 and cellular response to interferon-beta and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051607 and defense response to virus and biological process this GO :0061507 and cyclic-GMP-AMP binding and molecular function this GO :0071360 and cellular response to exogenous dsRNA and biological process, transmembrane protein 173
Identity 27962
Gene TMEM173
Long gene name transmembrane protein 173
Synonyms FLJ38577 NET23 ERIS MPYS STING MITA
Synonyms name stimulator of interferon genes
Locus 5q31, 2
Discovery year 2006-08-24
Entrez gene record 340061
Pubmed identfication 21947006
RefSeq identity NM_198282
Havana BLAST/BLAT OTTHUMG00000129239

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