Name : TMEM173 Antibody, HRP Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2639556502
| Long name | HRP Conjugated, TMEM173 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | HRP Conjugated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TMEM173 |
| Specificity | This is a highly specific antibody against TMEM173 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 260-310/379 |
| Subcellular location | Intracellular |
| Source | KLH conjugated synthetic peptide derived from human TMEM173 |
| Gene ID number | 340061 |
| Swiss Prot | Q86WV6 |
| Tested applications | IHC-P |
| Recommended dilutions | IHC-P(1:100-500) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression, Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm, May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II), May be involved in translocon function, Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway, the translocon possibly being able to influence the induction of type I interferons, Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FLJ38577 NET23 ERIS MPYS STING MITA |
| Properties | Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase  |
| Gene target | TMEM173 Conjugated |
| Short name | Conjugated, TMEM173 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | HRP |
| Alternative name | horseradish peroxidase coupled, transmembrane protein 173 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Plasma membranes, TMEM173 and IDBG-47893 and ENSG00000184584 and 340061, TMEM173 and IDBG-646026 and ENSBTAG00000002296 and 533661, Tmem173 and IDBG-137341 and ENSMUSG00000024349 and 72512, cyclic-GMP-AMP binding, this GO :0002218 and activation of innate immune response and biological process this GO :0002230 and positive regulation of defense response to virus by host and biological process this GO :0005515 and protein binding and molecular function this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005777 and peroxisome and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032092 and positive regulation of protein binding and biological process this GO :0032479 and regulation of type I interferon production and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032608 and interferon-beta production and biological process this GO :0033160 and positive regulation of protein import into nucleus, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019901: protein kinase binding and also this GO :0031625: ubiquitin protein ligase binding and also this GO :0035438: cyclic-di-GMP binding and also this GO :0042802: identical protein binding and also this GO :0042803: protein homodimerization activity and also this GO :0061507: cyclic-GMP-AMP binding, this GO :0008134: transcription factor binding, this GO :0019901: protein kinase binding, this GO :0031625: ubiquitin protein ligase binding, this GO :0035438: cyclic-di-GMP binding, this GO :0042802: identical protein binding, this GO :0042803: protein homodimerization activity, this GO :0061507: cyclic-GMP-AMP binding, translocation and biological process this GO :0035438 and cyclic-di-GMP binding and molecular function this GO :0035458 and cellular response to interferon-beta and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0042993 and positive regulation of transcription factor import into nucleus and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051607 and defense response to virus and biological process this GO :0061507 and cyclic-GMP-AMP binding and molecular function this GO :0071360 and cellular response to exogenous dsRNA and biological process, transmembrane protein 173 |
| Identity | 27962 |
| Gene | TMEM173 |
| Long gene name | transmembrane protein 173 |
| Synonyms name | stimulator of interferon genes |
| Locus | 5q31, 2 |
| Discovery year | 2006-08-24 |
| Entrez gene record | 340061 |
| Pubmed identfication | 21947006 |
| RefSeq identity | NM_198282 |
| Havana BLAST/BLAT | OTTHUMG00000129239 |