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TNIK (Ser764) Antibody

TNIK (Ser764) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTNIK (Ser764) Primary Polyclonal Antibody
Also known asTNIK (Ser764) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTNIK Ser764
Specificity Phosphorylation site corresponds to Ser735 in mouse, This is a highly specific antibody against TNIK Ser764
Modification(s)Phosphorylation
Modification site(s)Ser764
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range759-766/1360
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
Gene ID number23043
Swiss ProtQ9UKE5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Appears to act upstream of the JUN N-terminal pathway, May act by phosphorylating TCF4/TCF7L2, May play a role in the response to environmental stress, More generally, Part of a signaling complex composed of NEDD4, Phosphorylates SMAD1 on Thr-322, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Recruited to promoters of Wnt target genes and required to activate their expression, it may play a role in cytoskeletal rearrangements and regulate cell spreading, Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names KIAA0551, TNIK, TRAF2 and NCK-interacting protein kinase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTNIK (Ser764)
Short nameTNIK (Ser764) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTRAF2 and NCK interacting kinase (Ser764) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005083: small GTPase regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005083: small GTPase regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase
Identity 30765
Gene TNIK
Long gene name TRAF2 and NCK interacting kinase
Synonyms KIAA0551
Locus 3q26, 2-q26, 31
Discovery year 2004-02-26
GenBank acession AF172264
Entrez gene record 23043
Pubmed identfication 9628581 10521462
RefSeq identity XM_039796
Havana BLAST/BLAT OTTHUMG00000159036

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