Name : TNIK (Ser764) Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN9374677763
| Long name | ALEXA FLUOR 555 Conjugated, TNIK (Ser764) Polyclonal Antibody |
| Also known as | Anti-TNIK Ser764 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TNIK Ser764 |
| Specificity | This is a highly specific antibody against TNIK Ser764 |
| Modification | Phosphorylation |
| Modification Site | Ser764 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 759-766/1360 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764 |
| Gene ID Number | 23043 |
| Swiss Prot | Q9UKE5 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Appears to act upstream of the JUN N-terminal pathway, May act by phosphorylating TCF4/TCF7L2, May play a role in the response to environmental stress, More generally, Part of a signaling complex composed of NEDD4, Phosphorylates SMAD1 on Thr-322, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development, Recruited to promoters of Wnt target genes and required to activate their expression, it may play a role in cytoskeletal rearrangements and regulate cell spreading, Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | KIAA0551 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | TNIK (Ser764) |
| Short name | TNIK (Ser764) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, TRAF2 and NCK interacting kinase (Ser764) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627, TNIK and IDBG-64741 and ENSG00000154310 and 23043, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007256 and activation of JNKK activity and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005083: small GTPase regulator activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005083: small GTPase regulator activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048814 and regulation of dendrite morphogenesis and biological process this GO :0055037 and recycling endosome and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component, TRAF2 and NCK interacting kinase |
| Identity | 30765 |
| Gene | TNIK |
| Long gene name | TRAF2 and NCK interacting kinase |
| Locus | 3q26, 2-q26, 31 |
| Discovery year | 2004-02-26 |
| GenBank acession | AF172264 |
| Entrez gene record | 23043 |
| Pubmed identfication | 9628581 10521462 |
| RefSeq identity | XM_039796 |
| Havana BLAST/BLAT | OTTHUMG00000159036 |