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TNIP2 Antibody

TNIP2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTNIP2 Primary Polyclonal Antibody
Also known asTNIP2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTNIP2
SpecificityThis is a highly specific antibody against TNIP2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range200-230/430
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TNIP2/ABIN2
Gene ID number79155
Swiss ProtQ8NFZ5
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes, Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation, Involved in activation of the MEK/ERK signaling pathway during innate immune response, Involved in regulation of apoptosis in endothelial cells, May act as transcriptional coactivator when translocated to the nucleus, Required for stability of MAP3K8, promotes TEK agonist-stimulated endothelial survival, this function seems to be stimulus- and cell type specific, Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, ABIN2, FLIP1, Fetal liver LKB1-interacting protein, TNFAIP3-interacting protein 2, TNIP2, KLIP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTNIP2
Short nameTNIP2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTNFAIP3 interacting protein 2 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0023035 and CD40 signaling pathway and biological process this GO :0031593 and polyubiquitin binding and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0043032 and positive regulation of macrophage activation and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050821 and protein stabilization and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0070498 and interleukin-1-mediated signaling pathway and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, TNIP2 and IDBG-643700 and ENSBTAG00000015126 and 100336382, TNIP2 and IDBG-7609 and ENSG00000168884 and 79155, Tnip2 and IDBG-155271 and ENSMUSG00000059866 and 231130, nuclei, polyubiquitin binding, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019901: protein kinase binding and also this GO :0031593: polyubiquitin binding, this GO :0019901: protein kinase binding, this GO :0031593: polyubiquitin binding, TNFAIP3 interacting protein 2
Identity 19118
Gene TNIP2
Long gene name TNFAIP3 interacting protein 2
Synonyms ABIN-2 MGC4289 KLIP FLIP1
Locus 4p16, 3
Discovery year 2002-10-03
GenBank acession BC002740
Entrez gene record 79155
Pubmed identfication 11390377 12933576
RefSeq identity NM_024309
Havana BLAST/BLAT OTTHUMG00000090267

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