Name : Torsin B Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2858577399
| Long name | Torsin B Primary Polyclonal Antibody |
| Also known as | Torsin B PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Torsin B |
| Specificity | This is a highly specific antibody against Torsin B |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin B |
| Tested Applications | IF(IHC-P), IHC-P |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Defects in the gene encoding TorsinB are associated with torsion dystonia, Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB contains two PKC (protein kinase C) phosphorylations sites, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development, Via its ability to regulate protein folding, a related family member, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FKSG18, TOR1B, TOR1B_HUMAN, Tor1b, Torsin 1B, Torsin family 1 member B, DQ1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Torsin B |
| Short name | Torsin B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Torsin B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11995 |
| Gene | TOR1B |
| Long gene name | torsin family 1 member B |
| Synonyms gene name | member B (torsin B) , torsin family 1 |
| Synonyms | DQ1 MGC4386 |
| Synonyms name | torsin B |
| Locus | 9q34, 11 |
| Discovery year | 2000-02-17 |
| GenBank acession | AF007872 |
| Entrez gene record | 27348 |
| Pubmed identfication | 9288096 10644435 |
| RefSeq identity | NM_014506 |
| Havana BLAST/BLAT | OTTHUMG00000020795 |