Name : Torsin B Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN5734924867
| Long name | ALEXA FLUOR 488 Conjugated, Torsin B Polyclonal Antibody |
| Also known as | Anti-Torsin B PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Torsin B |
| Specificity | This is a highly specific antibody against Torsin B |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Torsin B |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in the gene encoding TorsinB are associated with torsion dystonia, Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB contains two PKC (protein kinase C) phosphorylations sites, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development, Via its ability to regulate protein folding, a related family member, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | DQ1 MGC4386 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Torsin B Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | Torsin B |
| Short name | Torsin B Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Torsin B (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11995 |
| Gene | TOR1B |
| Long gene name | torsin family 1 member B |
| Synonyms gene name | member B (torsin B) , torsin family 1 |
| Synonyms name | torsin B |
| Locus | 9q34, 11 |
| Discovery year | 2000-02-17 |
| GenBank acession | AF007872 |
| Entrez gene record | 27348 |
| Pubmed identfication | 9288096 10644435 |
| RefSeq identity | NM_014506 |
| Havana BLAST/BLAT | OTTHUMG00000020795 |