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TP73 Antibody

TP73 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTP73
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, WB, IHC
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:50-1:100, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the p73 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis p73 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O15350
PurityAntigen affinity
Description The family members can interact with each other in many ways involving direct or indirect protein interactions, The family members include p53, The p73 protein is expressed at very low levels in normal tissues and is differentially expressed in a number of tumors, and p73 and have high sequence similarity to one another, p63, resulting in regulation of the same target gene promoters or regulation of each other's promoters, which allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis, which is a member of the p53 family of transcription factors involved in cellular responses to stress and development, TP73 is tumor protein p73
ImmunogenA portion of amino acids 288-317 from the human protein was used as the immunogen for this p73 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p73 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTP73
Short nameTP73 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nametumor protein p73 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006954 and inflammatory response and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006978 and DNA damage response, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048546 and digestive tract morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048714 and positive regulation of oli this GO dendrocyte differentiation and biological process this GO :0051262 and protein tetramerization and biological process this GO :1902167 and positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :2001235 and positive regulation of apoptotic signaling pathway and biological process, P73, TP73 and IDBG-634515 and ENSBTAG00000005812 and 515105, TP73 and IDBG-86757 and ENSG00000078900 and 7161, Trp73 and IDBG-206900 and ENSMUSG00000029026 and 22062, metal ion binding, nuclei, signal transduction by p53 class mediator resulting in transcription of p21 class mediator and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010165 and response to X-ray and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0021766 and hippocampus development and biological process this GO :0030900 and forebrain development and biological process this GO :0031571 and mitotic G1 DNA damage checkpoint and biological process this GO :0033326 and cerebrospinal fluid secretion and biological process this GO :0034644 and cellular response to UV and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043508 and negative regulation of JUN kinase activity and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045793 and positive regulation of cell size and biological process this GO :0045893 and positive regulation of transcription, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000187 and activation of MAPK activity and biological process this GO :0000785 and chromatin and cellular component this GO :0001822 and kidney development and biological process this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0002039 and p53 binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005829 and cytosol and cellular component this GO :0006298 and mismatch repair and biological process this GO :0006351 and transcription, this GO :0002039: p53 binding, this GO :0002039: p53 binding and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003684: damaged DNA binding and also this GO :0003690: double-stranded DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008134: transcription factor binding and also this GO :0019901: protein kinase binding and also this GO :0042802: identical protein binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003684: damaged DNA binding, this GO :0003690: double-stranded DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008134: transcription factor binding, this GO :0019901: protein kinase binding, this GO :0042802: identical protein binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, tumor protein p73
Identity 12003
Gene TP73
Long gene name tumor protein p73
Synonyms P73
Locus 1p36, 32
Discovery year 1997-11-12
GenBank acession AB055065
Entrez gene record 7161
Pubmed identfication 9296498 9288759
RefSeq identity NM_005427
Havana BLAST/BLAT OTTHUMG00000000610

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