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TPOR Antibody

TPOR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTPOR Primary Polyclonal Antibody
Also known asTPOR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTPOR
SpecificityThis is a highly specific antibody against TPOR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TPOR
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Expression of c-Mpl is restricted to hematopoietic tissues and cells, Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, TPO exerts its biological effects through the TPO receptor, Tyk 2 and JAK2, also known as c-Mpl ligand (c-Mpl L), c-Mpl, c-Mpl is a member of the cytokine receptor superfamily, causing their nuclear translocation and the transcription of Stat responsive genes, fetal liver and CD34+ cells, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome, is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells, spleen, such as bone marrow, which in turn phosphorylate Stat5 and Stat3, Thrombopoietin (TPO or THPO)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C-MPL, CD 110, CD110, CMPL, MPL, MPLV, Myeloprolerative leukemia protein, Myeloprolerative leukemia virus oncogene, Proto-oncogene c-Mpl, THCYT2, TPO R, TPO-R, TPOR, TPOR_HUMAN, Thrombopoietin receptor, C MPL
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTPOR
Short nameTPOR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTPOR (Antibody to)
Alternative techniqueantibodies
Identity 7217
Gene MPL
Long gene name MPL proto-oncogene, thrombopoietin receptor
Synonyms gene name myeloproliferative leukemia virus oncogene
Synonyms CD110 TPOR
Locus 1p34, 2
Discovery year 1990-09-10
GenBank acession M90102
Entrez gene record 4352
Pubmed identfication 1608974
RefSeq identity NM_005373
Classification CD molecules Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000007429
Locus Specific Databases LRG_510

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