Name : TPOR Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1444810286
| Long name | ALEXA FLUOR 350 Conjugated, TPOR Polyclonal Antibody |
| Also known as | Anti-TPOR PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | TPOR |
| Specificity | This is a highly specific antibody against TPOR |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TPOR |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Expression of c-Mpl is restricted to hematopoietic tissues and cells, Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, TPO exerts its biological effects through the TPO receptor, Tyk 2 and JAK2, also known as c-Mpl ligand (c-Mpl L), c-Mpl, c-Mpl is a member of the cytokine receptor superfamily, causing their nuclear translocation and the transcription of Stat responsive genes, fetal liver and CD34+ cells, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome, is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells, spleen, such as bone marrow, which in turn phosphorylate Stat5 and Stat3, Thrombopoietin (TPO or THPO) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | CD110 TPOR |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | TPOR |
| Short name | TPOR Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, TPOR (Antibody to) |
| Alternative technique | antibodies |
| Identity | 7217 |
| Gene | MPL |
| Long gene name | MPL proto-oncogene, thrombopoietin receptor |
| Synonyms gene name | myeloproliferative leukemia virus oncogene |
| Locus | 1p34, 2 |
| Discovery year | 1990-09-10 |
| GenBank acession | M90102 |
| Entrez gene record | 4352 |
| Pubmed identfication | 1608974 |
| RefSeq identity | NM_005373 |
| Classification | CD molecules Fibronectin type III domain containing |
| Havana BLAST/BLAT | OTTHUMG00000007429 |
| Locus Specific Databases | LRG_510 |