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TPOR Antibody, PE Conjugated

TPOR Antibody, PE Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name PE Conjugated, TPOR Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationPE
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenTPOR
SpecificityThis is a highly specific antibody against TPOR
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human TPOR
Tested applicationsFCM
Recommended dilutionsFCM(1:20-100)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Expression of c-Mpl is restricted to hematopoietic tissues and cells, Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, TPO exerts its biological effects through the TPO receptor, Tyk 2 and JAK2, also known as c-Mpl ligand (c-Mpl L), c-Mpl, c-Mpl is a member of the cytokine receptor superfamily, causing their nuclear translocation and the transcription of Stat responsive genes, fetal liver and CD34+ cells, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome, is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells, spleen, such as bone marrow, which in turn phosphorylate Stat5 and Stat3, Thrombopoietin (TPO or THPO)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission480, 565nm/578nm
Synonyms CD110 TPOR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetTPOR PE Conjugated
Short name PE Conjugated, TPOR Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelPE
Alternative name peroxidase coupled, TPOR (Antibody to)
Alternative techniqueantibodies
Identity 7217
Gene MPL
Long gene name MPL proto-oncogene, thrombopoietin receptor
Synonyms gene name myeloproliferative leukemia virus oncogene
Locus 1p34, 2
Discovery year 1990-09-10
GenBank acession M90102
Entrez gene record 4352
Pubmed identfication 1608974
RefSeq identity NM_005373
Classification CD molecules Fibronectin type III domain containing
Havana BLAST/BLAT OTTHUMG00000007429
Locus Specific Databases LRG_510

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