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TPSAB1 Antibody

TPSAB1 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenTPSAB1
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the TPSAB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis TPSAB1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q15661
PurityAntigen affinity
Description Beta tryptases appear to be the main isoenzymes expressed in mast cells, Several tryptase genes are clustered on chromosome 16p13, The alleles of this gene exhibit an unusual amount of sequence variation, These genes are characterized by several distinct features, These genes have an intron immediately upstream of the initiator Met codon, They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability, This feature is characteristic of tryptases but is unusual in other genes, Tryptases are enzymatically active only as heparin-stabilized tetramers, Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders, alpha and beta 1, alpha tryptases predominate, and they are resistant to all known endogenous proteinase inhibitors, such that the alleles were once thought to represent two separate genes, the peptidase family S1, whereas in basophils, which separates the site of transcription initiation from protein coding sequence, 3, Tryptases comprise a family of trypsin-like serine proteases
ImmunogenA portion of amino acids 249-275 from the human protein was used as the immunogen for this TPSAB1 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the TPSAB1 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetTPSAB1
Short nameTPSAB1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTPSAB1 (Antibody to)
Alternative techniqueantibodies
Identity 12019
Gene TPSAB1
Long gene name tryptase alpha/beta 1
Synonyms gene TPSB1 TPS1 TPS2
Synonyms gene name tryptase beta 1
Synonyms name tryptase alpha II tryptase beta I tryptase-I tryptase-II tryptase-III
Locus 16p13, 3
Discovery year 1990-11-07
GenBank acession M33494
Entrez gene record 7177
Pubmed identfication 2203827 9920877
RefSeq identity NM_003294
Havana BLAST/BLAT OTTHUMG00000090467

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